Immunofluorescence studies on epidermal keratinization in some skin disorders with keratin antisera.
نویسندگان
چکیده
منابع مشابه
on some bayesian statistical models in actuarial science with emphasis on claim count
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15 صفحه اولSedimentation Studies of Epidermal Keratins. Keratin A and Keratin B
Electrophoretically homogeneous keratin A and keratin B were studied in the ultracentrifuge. Both preparations revealed two fractions: one which sedimented rapidly and another which sedimented slowly. This indicated that both preparations are heterogeneous with respect to particle size.
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Injury to epidermis and other stratified epithelia triggers profound but transient changes in the pattern of keratin expression. In postmitotic cells located at the wound edge, a strong induction of K6, K16, and K17 synthesis occurs at the expense of the keratins produced under the normal situation. The functional significance of these alterations in keratin expression is not known. Here, we re...
متن کاملKeratinization and its disorders.
Keratins are a diverse group of structural proteins that form the intermediate filament network responsible for maintaining the structural integrity of keratinocytes. In humans, there are around 30 keratin families divided into two groups, namely, acidic and basic keratins, which are arranged in pairs. They are expressed in a highly specific pattern related to the epithelial type and stage of c...
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Keratins K8 and K18 are the major components of the intermediate filament cytoskeleton of simple epithelia. Increased levels of these keratins have been associated with invasive growth and progression to malignancy in different types of human and murine epithelial tumors (including skin tumors), and even in tumors from nonepithelial origin. However, it has not yet clarified whether K8/K18 expre...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1983
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.141.163